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Anti-GDF11 Antibody (N-term)

Boster Bio Anti-GDF11 Antibody (N-term) (Catalog # A02355) . Tested in IHC-P, WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Synonyms

Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11, GDF11, BMP11

Gene Name

GDF11

UniProt

O95390

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GDF11.

Clonality

Polyclonal

Tissue Specificity

In the embryo, strong expression is seen in the palatal epithelia, including the medial edge epithelial and midline epithelial seam of the palatal shelves. Less pronounced expression is also seen throughout the palatal shelf and tongue mesenchyme

Applications

IHC-P, WB

Field of Research

Cell Biology, Neuroscience, Signal Transduction, Cytokines

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

3121511528257634

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

45091 Da

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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