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Anti-NSD1/Kmt3B Monoclonal Antibody

Boster Bio Anti-NSD1/Kmt3B Monoclonal Antibody catalog # A02327. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific;2.1.1.43; Androgen receptor coactivator 267 kDa protein; Androgen receptor-associated protein of 267 kDa; H3-K36-HMTase; H4-K20-HMTase; Lysine N-methyltransferase 3B; Nuclear receptor-binding SET domain-containing protein 1; NR-binding SET domain-containing protein; NSD1; ARA267, KMT3B

Gene Name

NSD1

UniProt

Q96L73

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant human NSD1 protein fragments expressed in E.coli.

Clonality

Monoclonal

Tissue Specificity

Expressed in the fetal/adult brain, kidney, skeletal muscle, spleen, and the thymus, and faintly in the lung.

Applications

WB

Purification

Protein A purified

Concentration

1 mg/mL

Form

Liquid

Function

Histone methyltransferase. Preferentially methylates 'Lys-36' of histone H3 and 'Lys-20' of histone H4 (in vitro) . Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

296652 MW

Gene Name Synonym

Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific

Subcellular Location

Nucleus. Chromosome .

Contents

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

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