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Anti-Alpha-1-antichymotrypsin SERPINA3 Antibody

Boster Bio Anti-Alpha-1-antichymotrypsin SERPINA3 Antibody catalog # A02312. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Alpha-1-antichymotrypsin; ACT; Cell growth-inhibiting gene 24/25 protein; Serpin A3; Alpha-1-antichymotrypsin His-Pro-less; SERPINA3; AACT; GIG24, GIG25

Gene Name

SERPINA3

UniProt

P01011

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human SERPINA3

Clonality

Polyclonal

Tissue Specificity

Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

47651 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Alpha-1-antichymotrypsin

Subcellular Location

Secreted.

Protein Name

Alpha-1-antichymotrypsin

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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