Anti-HIF-1 Beta ARNT Antibody
Boster Bio Anti-HIF-1 Beta ARNT Antibody catalog # A02263. Tested in WB, IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta; ARNT; BHLHE2
Gene Name
ARNT
UniProt
P27540
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein
Clonality
Polyclonal
Applications
WB, IHC
Purification
ProA affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity) . The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
86636 MW
Gene Name Synonym
Aryl hydrocarbon receptor nuclear translocator
Subcellular Location
Nucleus.
Protein Name
Aryl hydrocarbon receptor nuclear translocator
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
250323-APC 100 µL
POU5F2 (POU Domain Class 5, Transcription Factor 2, DKFZp686P02123, FLJ25680, SPRM-1) (APC)
Ask
View Details 