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Anti-HCN4 Antibody

Boster Bio Anti-HCN4 Antibody catalog # A02235. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; HCN4

Gene Name

HCN4

UniProt

Q9Y3Q4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 600-680

Clonality

Polyclonal

Tissue Specificity

Highly expressed in thalamus, testis and in heart, both in ventricle and atrium. Detected at much lower levels in amygdala, substantia nigra, cerebellum and hippocampus.

Applications

WB, ELISA

Purification

HCN4 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih) . May mediate responses to sour stimuli.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

129042 MW

Gene Name Synonym

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Subcellular Location

Cell membrane

Protein Name

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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