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Anti-NACA Antibody

Boster Bio Anti-NACA Antibody catalog # A02155. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Nascent polypeptide-associated complex subunit alpha; NAC-alpha; Alpha-NAC; Hom s 2; NACA; HSD48

Gene Name

NACA

UniProt

Q13765

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NACA

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER) . Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) . May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

23384 MW

Gene Name Synonym

Nascent polypeptide-associated complex subunit alpha

Subcellular Location

Cytoplasm. Nucleus. The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus.

Protein Name

Nascent polypeptide-associated complex subunit alpha

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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