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Anti-TREM2 Antibody

Boster Bio Anti-TREM2 Antibody catalog # A02150. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Triggering receptor expressed on myeloid cells 2; TREM-2; Triggering receptor expressed on monocytes 2; TREM2

Gene Name

TREM2

UniProt

Q9NZC2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord.

Applications

WB, ELISA

Purification

TREM2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

25447 MW

Gene Name Synonym

Triggering receptor expressed on myeloid cells 2

Subcellular Location

Isoform 1: Cell membrane

Protein Name

Triggering receptor expressed on myeloid cells 2

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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