Anti-OtoCadherin-23 CDH23 Antibody
Boster Bio Anti-OtoCadherin-23 CDH23 Antibody catalog # A02149. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Cadherin-23
Gene Name
CDH23
UniProt
Q9H251
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in Human CDH23
Clonality
Polyclonal
Tissue Specificity
Particularly strong expression in the retina (PubMed:11138009) . Found also in the cochlea.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
369494 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Cadherin-23
Subcellular Location
Cell membrane ; Single-pass type I membrane protein .
Protein Name
Cadherin-23
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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