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Anti-TREM-1 Antibody

Boster Bio Anti-TREM-1 Antibody catalog # A02135. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Triggering receptor expressed on myeloid cells 1; TREM-1; Triggering receptor expressed on monocytes 1; CD354; TREM1

Gene Name

TREM1

UniProt

Q9NP99

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from TREM-1 . at AA range: 40-120

Clonality

Polyclonal

Tissue Specificity

Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes. .

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

26387 MW

Gene Name Synonym

Triggering receptor expressed on myeloid cells 1

Subcellular Location

Isoform 1: Cell membrane ; Single-pass type I membrane protein .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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