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Anti-FHL2 Antibody

Boster Bio Anti-FHL2 Antibody catalog # A02129. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Four and a half LIM domains protein 2; FHL-2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; SLIM-3; FHL2; DRAL, SLIM3

Gene Name

FHL2

UniProt

Q14192

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human FHL2.

Clonality

Polyclonal

Tissue Specificity

Expressed in skeletal muscle and heart.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:28717008) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

32193 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Four and a half LIM domains protein 2

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line

Protein Name

Four and a half LIM domains protein 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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