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Anti-Glucokinase regulatory protein GCKR Antibody

Boster Bio Anti-Glucokinase regulatory protein GCKR Antibody catalog # A02122. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Glucokinase regulatory protein; GKRP; Glucokinase regulator; GCKR

Gene Name

GCKR

UniProt

Q14397

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Glucokinase Regulator. AA range:211-260

Clonality

Polyclonal

Tissue Specificity

Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

68685 MW

Gene Name Synonym

Glucokinase regulatory protein

Subcellular Location

Cytoplasm

Protein Name

Glucokinase regulatory protein

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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