Anti-ZMYND11 Antibody
Boster Bio Anti-ZMYND11 Antibody catalog # A02092. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Zinc finger MYND domain-containing protein 11 ; Adenovirus 5 E1A-binding protein; Bone morphogenetic protein receptor-associated molecule 1; Protein BS69; ZMYND11
Gene Name
ZMYND11
UniProt
Q15326
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human ZMYND11 (NP_997644.2) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity) . Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non- specifically to dsDNA (PubMed:24675531) . Acts as a tumor- suppressor by repressing a transcriptional program essential for tumor cell growth.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
70963 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Zinc finger MYND domain-containing protein 11
Subcellular Location
Nucleus
Protein Name
Zinc finger MYND domain-containing protein 11
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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