Anti-SMYD3 Antibody
Boster Bio Anti-SMYD3 Antibody catalog # A02080. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Histone-lysine N-methyltransferase SMYD3;2.1.1.43; SET and MYND domain-containing protein 3; Zinc finger MYND domain-containing protein 1; SMYD3; ZMYND1, ZNFN3A1
Gene Name
SMYD3
UniProt
Q9H7B4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human SMYD3 (NP_073580.1) .
Clonality
Polyclonal
Tissue Specificity
Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Histone methyltransferase. Specifically methylates 'Lys- 4' of histone H3, inducing di- and tri-methylation, but not monomethylation (PubMed:15235609, PubMed:22419068) . Also methylates 'Lys-5' of histone H4 (PubMed:22419068) . Plays an important role in transcriptional activation as a member of an RNA polymerase complex (PubMed:15235609) . Binds DNA containing 5'- CCCTCC-3' or 5'-GAGGGG-3' sequences (PubMed:15235609) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
49097 MW
Gene Name Synonym
Histone-lysine N-methyltransferase SMYD3
Subcellular Location
Cytoplasm
Protein Name
Histone-lysine N-methyltransferase SMYD3
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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