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Anti-SERPINF1 Antibody (Center)

Boster Bio Anti-SERPINF1 Antibody (Center) (Catalog # A02034-1) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

SERPINF1 is a member of the serpin family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity.

Synonyms

Pigment epithelium-derived factor, PEDF, Cell proliferation-inducing gene 35 protein, EPC-1, Serpin F1, SERPINF1, PEDF

Gene Name

SERPINF1

UniProt

P36955

Host

Rabbit

Reactivity

Human

Immunogen

This SERPINF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the Central region of human SERPINF1.

Clonality

Polyclonal

Tissue Specificity

Retinal pigment epithelial cells and blood plasma.

Applications

WB, Flow Cytometry, IHC-P

Field of Research

Cancer, Cardiovascular, Neuroscience

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

46312 Da

Subcellular Location

Secreted. Melanosome. Note=Enriched in stage I melanosomes

Prediction Reactivity

Bovine, Mouse

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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