Anti-TBC1D4 (phospho-T642) Antibody
Boster Bio Anti-TBC1D4 (phospho-T642) Antibody catalog # A02004T642. Tested in WB, IHC, IF applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
TBC1 domain family member 4; Akt substrate of 160 kDa; AS160; TBC1D4; AS160, KIAA0603
Gene Name
TBC1D4
UniProt
O60343
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthetic phosphopeptide derived from human TBC1D4 around the phosphorylation site of Threonine 642.
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Isoform 2 is the highest overexpressed in most tissues. Isoform 1 is highly expressed in skeletal muscle and heart, but was not detectable in the liver nor in adipose tissue. Isoform 2 is strongly expressed in adrenal and thyroid gland, and also in lung, kidney, colon, brain and adipose tissue. Isoform 2 is moderately expressed in skeletal muscle. Expressed in pancreatic Langerhans islets, including beta cells (at protein level) . Expression is decreased by twofold in pancreatic islets in type 2 diabetes patients compared to control subjects. Up-regulated in T-cells from patients with atopic dermatitis.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
146563 MW
Gene Name Synonym
TBC1 domain family member 4
Subcellular Location
Cytoplasm
Protein Name
TBC1 domain family member 4
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15090635 1 Vial
Lentiviral human RASGUAS shRNA (UAS) - Lentiviral human RASGUAS shRNA (UAS, RFP) (25)
Ask
View Details 
