Anti-Atlastin-1 ATL1 Antibody
Boster Bio Anti-Atlastin-1 ATL1 Antibody catalog # A01994. Tested in WB, IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Atlastin-1;3.6.5.-; Brain-specific GTP-binding protein; GTP-binding protein 3; GBP-3; hGBP3; Guanine nucleotide-binding protein 3; Spastic paraplegia 3 protein A; ATL1; GBP3, SPG3A
Gene Name
ATL1
UniProt
Q8WXF7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant full length Human ATL1.
Clonality
Polyclonal
Tissue Specificity
Expressed predominantly in the adult and fetal central nervous system. Measurable expression in all tissues examined, although expression in adult brain is at least 50-fold higher than in other tissues. Detected predominantly in pyramidal neurons in the cerebral cortex and the hippocampus of the brain. Expressed in upper and lower motor neurons (at protein level) .
Applications
WB, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (PubMed:27619977) . May also regulate Golgi biogenesis. May regulate axonal development.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
63544 MW
Gene Name Synonym
Atlastin-1
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Atlastin-1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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