Anti-Gab 1 (phospho-Y627) Antibody
Boster Bio Anti-Gab 1 (phospho-Y627) Antibody catalog # A01989Y627. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
GRB2-associated-binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1; GAB1
Gene Name
GAB1
UniProt
Q13480
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic phosphopeptide derived from human Gab 1 around the phosphorylation site of Tyrosine 627.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR) . Involved in the MET/HGF-signaling pathway (PubMed:29408807) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
76616 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
GRB2-associated-binding protein 1
Protein Name
GRB2-associated-binding protein 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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