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Anti-Gab 1 (phospho-Y627) Antibody

Boster Bio Anti-Gab 1 (phospho-Y627) Antibody catalog # A01989Y627. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

GRB2-associated-binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1; GAB1

Gene Name

GAB1

UniProt

Q13480

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic phosphopeptide derived from human Gab 1 around the phosphorylation site of Tyrosine 627.

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR) . Involved in the MET/HGF-signaling pathway (PubMed:29408807) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

76616 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

GRB2-associated-binding protein 1

Protein Name

GRB2-associated-binding protein 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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