Anti-GPBAR1 Antibody
Boster Bio Anti-GPBAR1 Antibody catalog # A01958. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37; GPBAR1; TGR5
Gene Name
GPBAR1
UniProt
Q8TDU6
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in Human GPBAR1
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon, cecum and liver, but not in esophagus and rectum.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
35248 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
G-protein coupled bile acid receptor 1
Subcellular Location
Cell membrane
Protein Name
G-protein coupled bile acid receptor 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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