Anti-GABARAP GABARAPL2 Antibody
Boster Bio Anti-GABARAP GABARAPL2 Antibody catalog # A01927. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Gamma-aminobutyric acid receptor-associated protein-like 2; GABA (A) receptor-associated protein-like 2; Ganglioside expression factor 2; GEF-2; General protein transport factor p16; Golgi-associated ATPase enhancer of 16 kDa; GATE-16; MAP1 light chain 3-related protein; GABARAPL2; FLC3A, GEF2
Gene Name
GABARAPL2
UniProt
P60520
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic Peptide of GABARAP AA range: 26-75
Tissue Specificity
Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine. .
Applications
WB, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity) . Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
13667 MW
Gene Name Synonym
Gamma-aminobutyric acid receptor-associated protein-like 2
Subcellular Location
Golgi apparatus . Cytoplasmic vesicle, autophagosome .
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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