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Anti-TH Antibody (C-term)

Boster Bio Anti-TH Antibody (C-term) (Catalog # A01917) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons.

Synonyms

Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH, TH, TYH

Gene Name

TH

UniProt

P07101

Host

Rabbit

Reactivity

Human

Immunogen

This TH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 486-514 amino acids from the C-terminal region of human TH.

Clonality

Polyclonal

Tissue Specificity

Mainly expressed in the brain and adrenal glands.

Applications

WB, Flow Cytometry, IHC-P

Field of Research

Cancer, Metabolism, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

1739106316801281528790385282103492220524753243

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

58600 Da

Subcellular Location

Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P24529}. Nucleus {ECO:0000250|UniProtKB:P04177} Cell projection, axon {ECO:0000250|UniProtKB:P24529}. Cytoplasm {ECO:0000250|UniProtKB:P04177}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:P04177}. Note=When phosphorylated at Ser-19 shows a nuclear distribution and when phosphorylated at Ser-31 as well at Ser-40 shows a cytosolic distribution (By similarity) . Expressed in dopaminergic axons and axon terminals. {ECO:0000250|UniProtKB:P04177}

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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