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Anti-CD88 C5AR1 Antibody

Boster Bio Anti-CD88 C5AR1 Antibody catalog # A01898. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD88; C5AR1; C5AR, C5R1

Gene Name

C5AR1

UniProt

P21730

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the N-terminal region of human C5AR1. AA range:1-50

Applications

WB, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520) . The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099) . Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

39336 MW

Gene Name Synonym

C5a anaphylatoxin chemotactic receptor 1

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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