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Anti-KIR2.1 KCNJ2 Antibody

Boster Bio Anti-KIR2.1 KCNJ2 Antibody catalog # A01850. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Inward rectifier potassium channel 2; Cardiac inward rectifier potassium channel; Inward rectifier K (+) channel Kir2.1; IRK-1; hIRK1; Potassium channel, inwardly rectifying subfamily J member 2; KCNJ2; IRK1

Gene Name

KCNJ2

UniProt

P63252

Host

Rabbit

Reactivity

Human, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human KCNJ2. AA range:81-130

Clonality

Polyclonal

Tissue Specificity

Heart, brain, placenta, lung, skeletal muscle, and kidney. Diffusely distributed throughout the brain.

Applications

WB, IHC, IF, ELISA

Purification

He antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

48288 MW

Gene Name Synonym

Inward rectifier potassium channel 2

Subcellular Location

Membrane; Multi-pass membrane protein. Membrane; Lipid-anchor .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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