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Anti-APOL1 Antibody

Boster Bio Anti-APOL1 Antibody (Catalog # A01841-2) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

APOL1 is a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver.

Synonyms

Apolipoprotein L1, Apolipoprotein L, Apo-L, ApoL, Apolipoprotein L-I, ApoL-I, APOL1, APOL

Gene Name

APOL1

UniProt

O14791

Host

Rabbit

Reactivity

Human

Immunogen

This APOL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-171 amino acids from human APOL1.

Clonality

Polyclonal

Tissue Specificity

Plasma. Found on APOA-I-containing high density lipoprotein (HDL3) . Expressed in pancreas, lung, prostate, liver, placenta and spleen

Applications

WB, Flow Cytometry, IHC-P

Field of Research

Cardiovascular, Metabolism

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

43974 Da

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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