Anti-ROR2 Antibody
Boster Bio Anti-ROR2 Antibody catalog # A01840. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Tyrosine-protein kinase transmembrane receptor ROR2;2.7.10.1
Gene Name
ROR2
UniProt
Q01974
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human ROR2 (NP_004551.2) .
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity) . Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073) . In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
104757 MW
Gene Name Synonym
Tyrosine-protein kinase transmembrane receptor ROR2
Subcellular Location
Cell membrane ; Single-pass type I membrane protein .
Protein Name
Tyrosine-protein kinase transmembrane receptor ROR2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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