Anti-NMDA Zeta 1 (phospho-S896) GRIN1 Antibody
Boster Bio Anti-NMDA Zeta 1 (phospho-S896) GRIN1 Antibody catalog # A01808S896. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Glutamate receptor ionotropic, NMDA 1; GluN1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; GRIN1; NMDAR1
Gene Name
GRIN1
UniProt
Q05586
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human NMDAζ1 around the phosphorylation site of Serine 896.
Clonality
Polyclonal
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg (2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280) . Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
105373 MW
Applications Notes
IHC: 1:50-1:200
Gene Name Synonym
Glutamate receptor ionotropic, NMDA 1
Subcellular Location
Cell membrane
Protein Name
Glutamate receptor ionotropic, NMDA 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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