Anti-UCN (A103) Antibody
Boster Bio Anti-UCN (A103) Antibody catalog # A01807. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Urocortin; UCN
Gene Name
UCN
UniProt
P55089
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 80-130 of Human UCN.
Clonality
Polyclonal
Tissue Specificity
Keratinocytes in epidermis and the outer and inner root sheaths of hair follicles, epithelium of sebaceous and sweat glands, erector pili muscle, cutaneous blood vessel walls, cutaneous nerves and dermal mononuclear cells (PubMed:10690896) . Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) (at protein level) . Expressed in pituitary and adrenal glands (PubMed:10690896) . Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) .
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed:8612563) . Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (PubMed:8612563) . Plays a role in the establishment of normal hearing thresholds (By similarity) . Reduces food intake and regulates ghrelin levels in gastric body and plasma (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
13458 MW
Gene Name Synonym
Urocortin
Subcellular Location
Secreted.
Protein Name
Urocortin
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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