Anti-Transcription factor E3 TFE3 Antibody
Boster Bio Anti-Transcription factor E3 TFE3 Antibody catalog # A01791. Tested in WB, IHC, ICC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33; TFE3; BHLHE33
Gene Name
TFE3
UniProt
P19532
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 133-178 of Human TFE3.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous in fetal and adult tissues.
Applications
WB, IHC, ICC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') . Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4 (+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
61521 MW
Gene Name Synonym
Transcription factor E3
Subcellular Location
Nucleus.
Protein Name
Transcription factor E3
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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