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Anti-MYPT1 (phospho-T696) PPP1R12A Antibody

Boster Bio Anti-MYPT1 (phospho-T696) PPP1R12A Antibody catalog # A01743T696. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit; PPP1R12A

Gene Name

PPP1R12A

UniProt

O14974

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide derived from human MYPT1 around the phosphorylation site of T696.

Clonality

Polyclonal

Tissue Specificity

Expressed in striated muscles, specifically in type 2a fibers (at protein level) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Key regulator of protein phosphatase 1C (PPP1C) . Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

115281 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Protein phosphatase 1 regulatory subunit 12A

Subcellular Location

Cytoplasm

Protein Name

Protein phosphatase 1 regulatory subunit 12A

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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