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Anti-MYPT1 (R690) PPP1R12A Antibody

Boster Bio Anti-MYPT1 (R690) PPP1R12A Antibody catalog # A01743. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit; PPP1R12A

Gene Name

PPP1R12A

UniProt

O14974

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 671-720 of Human MYPT1.

Clonality

Polyclonal

Tissue Specificity

Expressed in striated muscles, specifically in type 2a fibers (at protein level) .

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Key regulator of protein phosphatase 1C (PPP1C) . Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

115281 MW

Gene Name Synonym

Protein phosphatase 1 regulatory subunit 12A

Subcellular Location

Cytoplasm

Protein Name

Protein phosphatase 1 regulatory subunit 12A

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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