Anti-CYP4F2 Antibody

Phylloquinone omega-hydroxylase CYP4F2 ;1.14.13.194 ;20-hydroxyeicosatetraenoic acid synthase ;20-HETE synthase ;1.14.13.- ; Arachidonic acid omega-hydroxylase ; CYPIVF2; Cytochrome P450 4F2; Cytochrome P450-LTB-omega; Leukotriene-B (4) 20-monooxygenase 1; Leukotriene-B (4) omega-hydroxylase 1 ;1.14.13.30 ; CYP4F2

Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531) . Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070) . Also acts as a leukotriene-B (4) omega-hydroxylase by mediating conversion of leukotriene-B (4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene- B (4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565) . .