Anti-IFN-Gamma R Alpha (phospho-Y457) IFNGR1 Antibody
Boster Bio Anti-IFN-Gamma R Alpha (phospho-Y457) IFNGR1 Antibody catalog # A01716Y457. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Interferon gamma receptor 1
Gene Name
IFNGR1
UniProt
P15260
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human IFN-γRα around the phosphorylation site of Tyrosine 457.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460) . Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114) . Plays an essential role in the IFN-gamma pathway that is required for the cellular response to infectious agents (PubMed:20015550) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
54405 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Interferon gamma receptor 1
Subcellular Location
Cell membrane
Protein Name
Interferon gamma receptor 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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