Anti-CD32-B FCGR2B Antibody
Boster Bio Anti-CD32-B FCGR2B Antibody catalog # A01690. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32; FCGR2B; CD32, FCG2, IGFR2
Gene Name
FCGR2B
UniProt
P31994
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human FCGR2B (NP_003992.3) .
Clonality
Polyclonal
Tissue Specificity
Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells) . Not detected in natural killer cells.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
34044 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Low affinity immunoglobulin gamma Fc region receptor II-b
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-b
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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