Anti-DNA Ligase IV LIG4 Antibody
Boster Bio Anti-DNA Ligase IV LIG4 Antibody catalog # A01685. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
DNA ligase 4;6.5.1.1; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4; LIG4
Gene Name
LIG4
UniProt
P49917
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human DNL4. AA range:591-640
Tissue Specificity
Testis, thymus, prostate and heart.
Applications
WB, IHC, IF, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Efficiently joins single-strand breaks in a double- stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA- dependent protein kinase complex DNA-PK to these DNA ends. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
103971 MW
Gene Name Synonym
DNA ligase 4
Subcellular Location
Nucleus.
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040096-500 1x 500 µL
Histone H1 (AE-4), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042216-500 1x 500 µL
CD50 / ICAM3 (CG106), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682848-100 1x 100 µL
Fibronectin (Fn-3), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680034-100 1x 100 µL
Cytokeratin 8/18 (C-51), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402348-500 1x 500 µL
Neurofilament (NF-H) (Neuronal Marker) (rNF421), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details