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Anti-ENaC beta SCNN1B Antibody

Boster Bio Anti-ENaC beta SCNN1B Antibody catalog # A01670. Tested in IHC, IF, WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Amiloride-sensitive sodium channel subunit beta; Beta-NaCH; Epithelial Na (+) channel subunit beta; Beta-ENaC; ENaCB; Nonvoltage-gated sodium channel 1 subunit beta; SCNEB; SCNN1B

Gene Name

SCNN1B

UniProt

P51168

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Nonvoltage-gated Sodium Channel 1. AA range:581-630

Clonality

Polyclonal

Tissue Specificity

Detected in placenta, lung and kidney (PubMed:7762608) . Expressed in kidney (at protein level) (PubMed:22207244) .

Applications

IHC, IF, WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

72659 MW

Gene Name Synonym

Amiloride-sensitive sodium channel subunit beta

Subcellular Location

Apical cell membrane

Protein Name

Amiloride-sensitive sodium channel subunit beta

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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