Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-LAT (L185) Antibody

Boster Bio Anti-LAT (L185) Antibody catalog # A01654. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Linker for activation of T-cells family member 1;36 kDa phospho-tyrosine adapter protein; pp36; p36-38; LAT

Gene Name

LAT

UniProt

O43561

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 161-210 of Human LAT.

Clonality

Polyclonal

Tissue Specificity

Expressed in thymus, T-cells, NK cells, mast cells and, at lower levels, in spleen. Present in T-cells but not B-cells (at protein level) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Required for TCR (T-cell antigen receptor) - and pre-TCR- mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III) -mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

27930 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Linker for activation of T-cells family member 1

Subcellular Location

Cell membrane

Protein Name

Linker for activation of T-cells family member 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

PAQR8 Protein Vector (Rat) (pPM-C-His)
PV292401 500 ng

PAQR8 Protein Vector (Rat) (pPM-C-His)

Sign In for Pricing
View Details
KW-2478
MBS579099 Inquire

KW-2478

Sign In for Pricing
View Details
Nori® Salmon BMP4 ELISA Kit
GR202058 96 Well

Nori® Salmon BMP4 ELISA Kit

Sign In for Pricing
View Details
CDC42 (NM_044472) Human Tagged Lenti ORF Clone
RC216559L4 10 µg

CDC42 (NM_044472) Human Tagged Lenti ORF Clone

Sign In for Pricing
View Details
FITC-linked Antibody to High Mobility Group Protein 1 (HMG1)
MBS2015386-01 0.1 mL

FITC-linked Antibody to High Mobility Group Protein 1 (HMG1)

Sign In for Pricing
View Details
FITC-linked Antibody to High Mobility Group Protein 1 (HMG1)
MBS2015386-02 0.2 mL

FITC-linked Antibody to High Mobility Group Protein 1 (HMG1)

Sign In for Pricing
View Details