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Anti-OREX HCRT Antibody

Boster Bio Anti-OREX HCRT Antibody catalog # A01633. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Orexin; Hypocretin; Hcrt; Orexin-A; Hypocretin-1; Hcrt1; Orexin-B; Hypocretin-2; Hcrt2; HCRT; OX, PPORX, PPOX

Gene Name

HCRT

UniProt

O43612

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 21-70

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in subthalamic nucleus but undetectable in other brain regions tested (hypothalamus was not tested) and in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Applications

WB, ELISA

Purification

OREX antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

13363 MW

Gene Name Synonym

Orexin

Subcellular Location

Rough endoplasmic reticulum . Cytoplasmic vesicle . Cell junction, synapse . Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. .

Protein Name

Orexin

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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