Anti-Dynamin II DNM2 Monoclonal Antibody
Boster Bio Anti-Dynamin II DNM2 Monoclonal Antibody catalog # A01629. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Dynamin-2;3.6.5.5; DNM2; DYN2
Gene Name
DNM2
UniProt
P50570
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of Dynamin II expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 5E4C2F3
Tissue Specificity
Ubiquitously expressed.
Applications
WB, IHC, IF, ELISA
Purification
Ascitic fluid
Concentration
1 mg/mL
Form
Liquid
Function
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity) . Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis (PubMed:12498685) . Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
98064 MW
Gene Name Synonym
Dynamin-2
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cell junction . Membrane, clathrin-coated pit . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Midbody. Cell projection, phagocytic cup . Cytoplasmic vesicle, phagosome membrane ; Peripheral membrane protein . Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity) . Microtubule-associated. Also found in the postsynaptic density of neuronal cells. Co-localizes with PIK3C3 and RAB5A to the nascent phagosome (By similarity) . .
Contents
Ascitic fluid containing 0.03% sodium azide.
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