Anti-MIP-beta CCL19 Antibody
Boster Bio Anti-MIP-beta CCL19 Antibody catalog # A01605. Tested in IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
C-C motif chemokine 19; Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible cytokine A19; CCL19; ELC, MIP3B, SCYA19
Gene Name
CCL19
UniProt
Q99731
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from MIP-3β . at AA range: 20-100
Clonality
Polyclonal
Tissue Specificity
Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
Applications
IHC, IF, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/mL
Form
Liquid
Function
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
10993 MW
Gene Name Synonym
C-C motif chemokine 19
Subcellular Location
Secreted.
Protein Name
C-C motif chemokine 19
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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