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Anti-SOCS2 Antibody

Boster Bio Anti-SOCS2 Antibody catalog # A01584. Tested in WB, ICC, IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Suppressor of cytokine signaling 2; SOCS-2; Cytokine-inducible SH2 protein 2; CIS-2; STAT-induced STAT inhibitor 2; SSI-2; SOCS2; CIS2, SSI2, STATI2

Gene Name

SOCS2

UniProt

O14508

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein within human SOCS2 1-150aa.

Clonality

Polyclonal

Tissue Specificity

High expression in heart, placenta, lung, kidney and prostate.

Applications

WB, ICC, IF, IP

Purification

ProA affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

22172 MW

Gene Name Synonym

Suppressor of cytokine signaling 2

Protein Name

Suppressor of cytokine signaling 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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