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Anti-AP-2 Gamma (A436) TFAP2C Antibody

Boster Bio Anti-AP-2 Gamma (A436) TFAP2C Antibody catalog # A01558. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Transcription factor AP-2 gamma; AP2-gamma; Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1; TFAP2C

Gene Name

TFAP2C

UniProt

Q92754

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 400-448 of Human AP-2γ.

Clonality

Polyclonal

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

49177 MW

Applications Notes

IHC: 1:50-1:200

Gene Name Synonym

Transcription factor AP-2 gamma

Subcellular Location

Nucleus

Protein Name

Transcription factor AP-2 gamma

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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