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Anti-MMP-12 (D411) Antibody

Boster Bio Anti-MMP-12 (D411) Antibody catalog # A01520. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Macrophage metalloelastase; MME;3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12; MMP12; HME

Gene Name

MMP12

UniProt

P39900

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to amino acids 400-450 of Human MMP-12.

Clonality

Polyclonal

Tissue Specificity

Found in alveolar macrophages but not in peripheral blood monocytes.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

54002 MW

Gene Name Synonym

Macrophage metalloelastase

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Protein Name

Macrophage metalloelastase

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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