Anti-GDF-9 Antibody
Boster Bio Anti-GDF-9 Antibody catalog # A01466. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Growth/differentiation factor 9; GDF-9; GDF9
Gene Name
GDF9
UniProt
O60383
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human GDF9 (NP_005251.1) .
Clonality
Polyclonal
Tissue Specificity
Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
51444 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Growth/differentiation factor 9
Subcellular Location
Secreted .
Protein Name
Growth/differentiation factor 9
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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