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Anti-GDF-9 Antibody

Boster Bio Anti-GDF-9 Antibody catalog # A01466. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Growth/differentiation factor 9; GDF-9; GDF9

Gene Name

GDF9

UniProt

O60383

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human GDF9 (NP_005251.1) .

Clonality

Polyclonal

Tissue Specificity

Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

51444 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Growth/differentiation factor 9

Subcellular Location

Secreted .

Protein Name

Growth/differentiation factor 9

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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