Anti-TNFR2 TNFRSF1B Antibody
Boster Bio Anti-TNFR2 TNFRSF1B Antibody catalog # A01437. Tested in WB, ICC/IF, IHC, Flow Cytometry, IP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD120b; Etanercept; Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2; TBP-2; TBPII; TNFRSF1B; TNFBR, TNFR2
Gene Name
TNFRSF1B
UniProt
P20333
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Applications
WB, ICC, IF, IHC, Flow Cytometry, IP
Purification
ProA affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
48291 MW
Gene Name Synonym
Tumor necrosis factor receptor superfamily member 1B
Subcellular Location
Isoform 1: Cell membrane; Single-pass type I membrane protein.
Protein Name
Tumor necrosis factor receptor superfamily member 1B
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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