Anti-SMRTe (K535) NCOR2 Antibody
Boster Bio Anti-SMRTe (K535) NCOR2 Antibody catalog # A01412. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Nuclear receptor corepressor 2 ; N-CoR2 ; CTG repeat protein 26; SMAP270; Silencing mediator of retinoic acid and thyroid hormone receptor ; SMRT ; T3 receptor-associating factor; TRAC; Thyroid-, retinoic-acid-receptor-associated corepressor; NCOR2
Gene Name
NCOR2
UniProt
Q9Y618
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 505-565 of Human SMRTe.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous. High levels of expression are detected in lung, spleen and brain.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Transcriptional corepressor (PubMed:20812024) . Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 4 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
273657 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Nuclear receptor corepressor 2
Subcellular Location
Nucleus.
Protein Name
Nuclear receptor corepressor 2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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