Anti-CD74 Antibody
Boster Bio Anti-CD74 Antibody catalog # A01340. Tested in WB, IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74; CD74; DHLAG
Gene Name
CD74
UniProt
P04233
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant full length Human CD74.
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
33516 MW
Gene Name Synonym
HLA class II histocompatibility antigen gamma chain
Subcellular Location
Cell membrane ; Single-pass type II membrane protein . Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.
Protein Name
HLA class II histocompatibility antigen gamma chain
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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