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Anti-CD141 THBD Antibody

Boster Bio Anti-CD141 THBD Antibody (Catalog# A01325) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM

Gene Name

THBD

UniProt

P07204

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant CD141 protein (amino acids 50-300)

Clonality

Polyclonal

Tissue Specificity

Endothelial cells are unique in synthesizing thrombomodulin.

Applications

WB

Field of Research

Cardiovascular, Stem Cells

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

60329 MW

Applications Notes

Western blot: 1-2 μg/ml

Gene Name Synonym

Thrombomodulin

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Thrombomodulin

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.

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