Anti-Cleaved-Factor XII HC (R372) F12 Antibody
Boster Bio Anti-Cleaved-Factor XII HC (R372) F12 Antibody catalog # A01226. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Coagulation factor XII;3.4.21.38; Hageman factor; HAF; Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain; Beta-factor XIIa part 2; F12
Gene Name
F12
UniProt
P00748
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human FA12. AA range:323-372
Applications
WB, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
67792 MW
Gene Name Synonym
Coagulation factor XII
Subcellular Location
Secreted.
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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