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Anti-FADS2 Antibody (Center)

Boster Bio Anti-FADS2 Antibody (Center) (Catalog # A01220-1) . Tested in IHC-P, WB, Flow Cytometry application (s) . This antibody reacts with Human.

Product Specifications

Background

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

Synonyms

Fatty acid desaturase 2, 11419-, Delta (6) fatty acid desaturase, D6D, Delta (6) desaturase, Delta-6 desaturase, FADS2

Gene Name

FADS2

UniProt

O95864

Host

Rabbit

Reactivity

Human

Immunogen

This FADS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-122 amino acids of human FADS2.

Clonality

Polyclonal

Tissue Specificity

Expressed in a wide array of tissues, highest expression is found in liver followed by brain, lung, heart, and retina. A lower level is found in breast tumor when compared with normal tissues; lowest levels were found in patients with poor prognostic index.

Applications

IHC-P, WB, Flow Cytometry

Field of Research

Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

1271357112713571

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

52259 Da

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Prediction Reactivity

Bovine, Xenopus

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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