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Anti-Cytochrome P450 2C8 CYP2C8 Antibody

Boster Bio Anti-Cytochrome P450 2C8 CYP2C8 Antibody catalog # A01179. Tested in IHC, IF, ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

Cytochrome P450 2C8;1.14.14.1

Gene Name

CYP2C8

UniProt

P10632

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human CYP2C8. AA range:241-290

Clonality

Polyclonal

Applications

IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti- cancer drug paclitaxel (taxol) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

55825 MW

Gene Name Synonym

Cytochrome P450 2C8

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Protein Name

Cytochrome P450 2C8

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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