Anti-IL-11 Monoclonal Antibody
Boster Bio Anti-IL-11 Monoclonal Antibody catalog # A01160. Tested in WB, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Interleukin-11; IL-11; Adipogenesis inhibitory factor ; AGIF ; Oprelvekin; IL11
Gene Name
IL11
UniProt
P20809
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human IL-11 expressed in E. Coli.
Clonality
Monoclonal
Applications
WB, ELISA
Purification
Protein A purified
Concentration
1 mg/mL
Form
Liquid
Function
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578) . Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066) . Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
21429 MW
Gene Name Synonym
Interleukin-11
Subcellular Location
Secreted .
Contents
Purified antibody in PBS containing 0.03% sodium azide.
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